Author(s): Aarti R. Sanap, Vikas G. Pawar

Email(s): aartisanap773@gmail.com , Pawarvicky9921@gmail.com

DOI: 10.52711/2349-2988.2026.00015   

Address: Aarti R. Sanap, Vikas G. Pawar
Pravara Rural College of Pharmacy, Loni 413736, Maharashtra, India.
*Corresponding Author

Published In:   Volume - 18,      Issue - 1,     Year - 2026


ABSTRACT:
Chewing gum can be used as a mobile drug delivery system for administering drugs locally or systematically via the oral cavity. Herbal chewing gum has gained acceptance as a drug delivery system due to its natural ingredients. A recent study aimed to investigate an herbal formulation for anti-ulcer activity. The study successfully formulated a medicated herbal chewing gum with anti-ulcer properties, using ingredients such as Ocimum sanctum (Tulsi), curry leaves, and the rhizome of Curcumin. The gum was found to be pale yellow with a sweet taste.


Cite this article:
Aarti R. Sanap, Vikas G. Pawar. Formulation and Evaluation of Herbal Mouth Ulcer Gum. Research Journal of Science and Technology. 2026; 18(1):100-4. doi: 10.52711/2349-2988.2026.00015

Cite(Electronic):
Aarti R. Sanap, Vikas G. Pawar. Formulation and Evaluation of Herbal Mouth Ulcer Gum. Research Journal of Science and Technology. 2026; 18(1):100-4. doi: 10.52711/2349-2988.2026.00015   Available on: https://www.rjstonline.com/AbstractView.aspx?PID=2026-18-1-15


REFERENCE: 
1.    Mahajan, A., and Gupta, M. (2021). Manifestations of Systemic Diseases in Oral cavity. Dentomed Publication House. 
2.    Yogarajah, Sangeetha; Setterfield, Jane. Mouth ulcers and diseases of the oral cavity. Medicine, 2021; 49(7): 407-413. 
3.    Sędzikowska, A., and Szablewski, L. (). Human gut microbiota in health and selected cancers. International Journal of Molecular Sciences. 2021; 22(24): 13440. 
4.    Ouahed, J., Spencer, E., Kotlarz, D., Shouval, D. S., Kowalik, M., Peng, K., and Snapper, S. B. Very early onset inflammatory bowel disease: a clinical approach with a focus on the role of genetics and underlying immune deficiencies. Inflammatory Bowel Diseases. 2020; 26(6): 820-842. 
5.    Kumar, J., Gupta, L., Gupta, M., and Gond, S. P. (2022). A Review on: Herbal Remedies for Treatment of Mouth Ulcer. 
6.    Galati, Alexandra, et al. Glucocorticoids for therapeutic immunosuppression: Clinical pearls for the practicing neurologist. Journal of the Neurological Sciences. 2021; 430: 120004. 
7.    Storz, Maximilian Andreas. Reduced diabetes medication needs with a plant-based diet. Journal of the American College of Nutrition 39.6 (2020): 574-577. 
8.    Bhovi, Venkatesh K. Plants based materials as the antifungal and antibacterial agents. International Journal of Plant Based Pharmaceuticals 2022; 2(1): 98-110. 
9.    Ding, Y., Zhu, Z., Zhang, X., and Wang, J. (2024). Novel Functional Dressing Materials for Intraoral Wound Care. Advanced Healthcare Materials, 2400912. 
10.    Banakar, M., Moayedi, S., Shamsoddin, E., Vahedi, Z., Banakar, M. H., Mousavi, S. M and Bagheri Lankarani, K. (2022). Chewing gums as a drug delivery approach for oral health. International Journal of Dentistry, 2022. 
11.    Sahu, Jyoti Kiran; Prasad, Suruchi. Recent Formulation Development Advances and Drug Delivery Insights for Medicated Chewing Gums. Int J Med Phar Sci. Vol, 2023; 13.1: 10. 
12.    EKOR, Martins. The growing use of herbal medicines: issues relating to adverse reactions and challenges in monitoring safety. Frontiers in Pharmacology. 2014; 4: 66193. 
13.    Al Shoyaib, Abdullah; Archie, Sabrina Rahman; Karamyan, Vardan T. Intraperitoneal route of drug administration: should it be used in experimental animal studies? Pharmaceutical Research. 2020; 37(1): 12. 
14.    Thivya, P., Durgadevi, M., and Sinija, V. R. N. (). Biodegradable medicated chewing gum: A modernized system for delivering bioactive compounds. Future Foods. 2021; 4: 100054. 
15.    Garg, Tarun; K Goyal, Amit. Medicated chewing gum: patient compliance oral drug delivery system. Drug Delivery Letters. 2014; 4(1): 72-78. 
16.    Thivya, P., Durgadevi, M., and Sinija, V. R. N.  Biodegradable medicated chewing gum: A modernized system for delivering bioactive compounds. Future Foods. 2021; 4: 100054. 
17.    Ames, J. P., Ail, P. D., Crasta, L., Kamath, R. S., Shura, M. H., and Sindhu, T. J. In silico ADMET and molecular interaction profiles of phytochemicals from medicinal plants in Dakshina Kannada. Journal of Health and Allied Sciences NU. 2024; 14(2): 190201. 
18.    Mohseni, F., Sharifi, I., Oliaee, R. T., Babaei, Z., Mostafavi, M., Almani, P. G. N., and Tavakoly, R. Antiproliferative properties of Turmerone on Leishmania major: Modes of action confirmed by antioxidative and immunomodulatory roles. Comparative Immunology, Microbiology and Infectious Diseases. 2022; 84: 101797. 
19.    Dhami, G., Paudel, S., and Sapkota, S. Effect of different processing methods on functional and physiochemical properties of turmeric (Curcuma longa Linn.) rhizome Var. Kapurkot Haledo-1. Eastern Journal of Agricultural and Biological Sciences. 2023; 3(3): 70-80. 
20.    Vinyagamoorthy, Sneha, et al. Pharmacological Effect of In Vitro Antioxidant Property and Green Synthesis of Silver Nanoparticles (AgNPs) Utilizing Murraya koenigii Antibacterial Application. Journal of Pharmacy and Bioallied Sciences. 2024; 16(Suppl 2): S1263-S1269. 
21.    Senn, Charles. Book of Sauces. Applewood Books, 2008. 
22.    Ajay, S., et al. Comprehensive review: Murraya koenigii Linn. Asian J Pharm Life Sci. 2011; 2231: 4423. 


Recomonded Articles:

Author(s): Rajendra K. Jangde

DOI: 10.5958/2349-2988.2015.00026.1         Access: Open Access Read More

Author(s): Sejal M. Karwa, Dattaprasad N. Vikhe, Ravindra S. Jadhav

DOI: 10.52711/2349-2988.2022.00042         Access: Open Access Read More

Author(s): A Bhoir, S. Borade, S. Borde, G. Chaudhari, T. Chaudhari, Proff. V. Sharma

DOI: 10.52711/2349-2988.2022.00027         Access: Open Access Read More

Author(s): Aarti R. Sanap, Vikas G. Pawar

DOI: 10.52711/2349-2988.2026.00015         Access: Closed Access Read More

Research Journal of Science and Technology (RJST) is an international, peer-reviewed journal, devoted to science and technology...... Read more >>>

RNI: Not Available                     
DOI: 10.5958/2349-2988 


Recent Articles




Tags